Page 9 - Valley Life & Health
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rima Duperval was enjoying a girls’ night
           out in August 2018, but behind her   To
      P laughter she was worried about a walnut-
       size lump she’d recently discovered in her right
       breast. “I was a little in denial,” she says.
          When she finally confided in her friends,
       they assured her it probably wasn’t serious.
       After all, she was just 31 with lots of energy
       and an exciting new job as a tech partner at
       Lehigh Valley Hospital–Cedar Crest. Still, they
       urged her to be smart and get it checked out.

       Diagnosis shock
          Duperval, who lives in Pocono Summit,
       Pa., made an appointment at nearby LVPG
       Obstetrics and Gynecology–Bartonsville.
       Results from an ultrasound and mammogram
       were inconclusive. Over the next week as she
       waited for her biopsy results, the lump began
       growing at an alarming rate.           individualize her treatment, Nair enrolled   intravenous treatments that drained her physically
          On Aug. 13, Duperval and her mother arrived   Duperval in a leading-edge clinical trial to uncover   but effectively shrank the tumor.
       for the biopsy results appointment. The news was   genetic mutations driving the cancer – one of      On Oct. 17, 2018, Duperval underwent
       bad – the lump was a sarcoma, a rare form of   many innovations available to patients through the   an elective double mastectomy with surgical
       aggressive cancer that can develop in soft tissues   Cancer Institute’s membership in the Memorial   oncologist Heiwon Chung, MD, with LVPG
       anywhere in the body. Duperval’s just happened   Sloan Kettering (MSK) Cancer Alliance.  Surgical Oncology, followed by another
       to form in her breast.                    “The advantage of being an Alliance member   chemotherapy round. Afterward, she began
          They immediately headed to Dale and   is that no matter how aggressive the cancer, we   radiation therapy with radiation oncologist
       Frances Hughes Cancer Center at Lehigh   can bring groundbreaking precision medicine   Charles Andrews, MD, at Hughes Cancer
       Valley Hospital–Pocono, where oncologist   right to where patients live,” Nair says.  Center. “We administered 30 radiation
       Suresh Nair, MD, with Lehigh Valley Cancer      Genetic testing results showed that   treatments to maximize local control and help
       Institute, had already been alerted. Breast   Duperval’s tumor cells had a BRCA1 (BReast   improve survival,” he says.
       cancer navigator Caroline McConnell, RN, and   CAncer) gene mutation, but the rest of her      Today, Duperval is cancer-free and recently
       nurse practitioner Lutchana Beckford, CRNP,   body’s cells were mutation-free, meaning she   enrolled in a nursing program. “If not for my
       were on hand to welcome them and answer   had no genetic risk factors for cancer.  medical team’s support I don’t think I’d be
       questions from the moment they arrived.     Encouraged by the results, her medical team   here,” she says. “I really want to give back now,
          “That day was overwhelming,” Duperval says,   agreed to treat the tumor as a sarcoma (not a   and this experience has pushed me to become
       “but everyone was so supportive.”      traditional breast tumor) using highly targeted   an oncology nurse.”
                                              chemotherapy drugs to inflict maximum DNA   Access to clinical trials
       Plan of attack                         damage to the mutated tumor cells. Afterward,      In 2016, Lehigh Valley Cancer Institute joined
          A positron emission tomography (PET) scan   Duperval would undergo surgery and radiation.  the Memorial Sloan Kettering (MSK) Cancer
       revealed that Duperval’s tumor had spread to                                  Alliance, created to bring world-class cancer care
       nearby lymph nodes but not to her organs.  Top-tier treatment                 to local communities. Benefits include:
          “At stage 3, we knew we had a shot at a cure,”     Between August and October of 2018,   • Cancer Institute specialists consult with MSK
       Nair says. “But the tumor had already grown from  Duperval received two rounds of “continuous   experts, keeping abreast of the latest treatment
       1 to 6 centimeters in under a month, so we had   infusion” chemotherapy, both requiring a   innovations and quickly adopting MSK standards
       to move fast and treat it aggressively.”  three-day hospital stay with round-the-clock   of care.
                                                                                     • Patients gain access to early clinical trials,
                                                                                     genetic tests and other care advances.
                                                                                     • Patients receive front-line cancer care close
                                                                                     to home.
                                                                                        Search clinical research trials at
                                                                                     LVHN.org/clinicaltrials.


                                                                                      Lehigh Valley Cancer Institute Locations
                                                                                      n  John and Dorothy Morgan Cancer Center
                                                                                        at Lehigh Valley Hospital – Cedar Crest
                                                                                      n LVHN Cancer Center at Lehigh Valley
                                                                                        Hospital – Muhlenberg
                                                                                      n  LVHN Cancer Center – Hazleton
                                                                                      n LVHN Cancer Center – Schuylkill
                                                                              Photos courtesy of  LVHN    at Lehigh Valley Hospital – Pocono
                                                                                      n Dale and Frances Hughes Cancer Center

                                                                                      n  LVPG Hematology Oncology – Bangor
                                                                                      n  LVPG Hematology Oncology – Lehighton
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